Our Approach

Cardiovascular and other diseases are manifest in the microcirculation years before they rise to a clinical level.


  • We use microvascular, cellular, molecular, proteomic and genomic bioengineering to analyze autodigestion mechanisms in disease, aging and death.
  • We design new interventions against autodigesion and translate these to human use.
  • The study of Autodigestion opens new opportunities for interventions and prevention of human diseases.





The research is funded by grants from the National Institute of Health, the National Science Foundation, the American Heart Association, the American Juvenile Diabetes Association, the European Union, and The UCSD Van Liebig Center.
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Microcirculation in Intestinal Villi